Paul Santoleri was born in Philadelphia. He earned his BFA in painting from Tyler School of Art and Architecture at Temple University in Philadelphia and Rome, Italy; an MFA in painting from the University of Arizona, Tucson; and attended the Skowhegan School of Painting & Sculpture, ME.
He has exhibited his work internationally at Think Tank Gallery, Los Angeles; Foundation Gallery, New Orleans; Galerie Ligne 13, Paris; Kentler International Drawing Space, Brooklyn, New York City; Galerie Nouveau, Santo Domingo, Dominican Republic; Pennsylvania Academy of the Fine Arts and Fleisher Art Memorial, Philadelphia; Kunstraum Kreuzberg, Berlin; Takatsuki Modern Theatre, Osaka, Japan; Galeria Aunkan, Barcelona, Spain; and the U.S. Embassy in Damascus, Syria.
His work is in the collections of Centro Cultural Norteamericano Nicaraguense,Managua, Nicaragua; Claremont College Consortium, CA; McDonald's’ Corporate Collection, King of Prussia, PA; Odermatt Collection, Paris and Montreal; Philadelphia Museum of Art; Rhode Island School of Design Museum, Providence; and the U.S. Embassy in Paris.
Santoleri received residencies at Chateau le Trousse Barriere, Briare, France; Islip Art Museum, East Islip, NY; Brandywine Workshop and Archives, Philadelphia; Montalvo Arts Center, Saratoga, CA; and Banff Centre for Arts and Creativity, Alberta, Canada. He received fellowships and grants from the Sharpe-Walentas Studio Program, Brooklyn, New York City; Independence Foundation, Philadelphia; Pollock-Krasner Foundation, New York City; John Michael Kohler Art Center, Sheboygan, WI; Pennsylvania Council on the Arts; and a fellowship at MacDowell, an artist colony in Peterborough, NH.