Mexican American painter, graphic artist, and muralist, Dolores Guerrero-Cruz was born in Rocky Ford, Colorado. She studied art at California State University in Los Angeles, the University of California in Davis, the University of California in Los Angeles, and Otis College of Art and Design in Los Angeles. Her work has been exhibited in institutions such as the Museum of Modern Art in New York, El Centro de la Raza in Santa Barbara, California; Galería Otra Vez in Los Angeles, California; Los Angeles County Museum, and Galería de La Raza in San Francisco, California.
Guerrero-Cruz has been active in both the Chicano and feminist movements most of her professional life. Her art reflects her advocacy towards the feminist movement and empowerment movement for the Chicano and Latin communities. While studying art at California State University, she began working with Self-Help Graphics an arts facility located in East Los Angeles, that helps artists flourish while contributing empowerment to the Latin community. She later became active with the art collective RCAF (Rebel Chicano Art Front, or Royal Chicano Air Force) in Sacramento, supporting the efforts of César Chávez and the United Farm Workers.
Aside from community work through the creation of city murals with art students, she was also a screen printing professor at Pasadena Community College. Guerrero contributed her skills towards local foundations including ARTS TEACH UCLA and the East Los Angeles Rape Hotline and Child Abuse Center. In January 1999, Guerrero-Cruz and co-founder Juan Gómez established Screen Print School and Canela Studio.